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SIRS Criteria

SIRS Criteria

Note: SIRS + suspected infection = Sepsis (by the 1992 ACCP/SCCM definition). The Sepsis-3 definition (2016) uses SOFA criteria instead.

SIRS Score

0

SIRS criteria NOT met

About

The Systemic Inflammatory Response Syndrome (SIRS) criteria identify patients with a systemic inflammatory response. Meeting ≥ 2 criteria defines SIRS. While SIRS is non-specific and can result from infection, trauma, burns, or pancreatitis, SIRS with a suspected source of infection was historically used to define sepsis (prior to Sepsis-3). The SIRS criteria remain widely used for early identification of critically ill patients.

Formula

SIRS Score = Sum of criteria met (0–4)
SIRS positive if ≥ 2 criteria are met

Interpretation

ScoreInterpretation
0 – 1SIRS criteria not met
2SIRS positive
3SIRS positive
4SIRS positive (all criteria met)

References

  1. Bone RC, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. Chest. 1992;101(6):1644-1655.
  2. Kaukonen KM, et al. Systemic inflammatory response syndrome criteria in defining severe sepsis. N Engl J Med. 2015;372(17):1629-1638.

FAQ

Related Calculators

SOFA

Assess organ dysfunction severity using the SOFA score.

qSOFA

Quick bedside screening for sepsis risk using the qSOFA score.

APACHE II

Estimate ICU mortality risk using the APACHE II scoring system.

Disclaimer

For educational and informational purposes only. Not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional.