HbA1c Calculator (A1c to eAG)
Convert HbA1c between NGSP percent and IFCC mmol/mol units and estimate average glucose in mg/dL and mmol/L using the ADAG equation, with diagnostic and assay limitations.
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Formula and medical content are based on the references listed on this page. See sources, About, and Sources and Review Process.
About
Formula
Interpretation
What HbA1c and eAG represent
A1C indirectly reflects glycation across red-cell survival over roughly 2–3 months, with greater weight from recent weeks. eAG is a regression translation from the ADAG study, not a glucose measured at the same time. Neither A1C nor eAG shows daily variability, post-meal peaks or hypoglycemia.
ADA diagnostic context for nonpregnant individuals
Below 5.7% NGSP or 39 mmol/mol IFCC is below the prediabetes threshold; 5.7–6.4% or 39–47 mmol/mol is the prediabetes range; and at least 6.5% or 48 mmol/mol is the diabetes diagnostic threshold. These thresholds require the appropriate clinical context and an NGSP-certified, DCCT-traceable laboratory method. In the absence of unequivocal hyperglycemia, diagnosis generally requires confirmatory testing. This page cannot establish a diagnosis.
Monitoring goals are individualized
ADA 2026 describes an A1C goal below 7% as appropriate for many nonpregnant adults, not everyone. Lower or less stringent goals depend on hypoglycemia risk, age, functional status, comorbidities, life expectancy, treatment burden and personal goals. This page does not recommend treatment changes.
A1C, CGM and measured glucose are different
A1C is indirect, and eAG comes from one 2008 study. Modern CGM mean glucose, GMI and eAG may differ. A1C does not report time in range, time below range, time above range or glycemic variability. BGM or CGM context is particularly important with insulin therapy or marked glucose variability.
Conditions that alter A1C interpretation
Hemolytic anemia, iron-deficiency anemia, acute or recent blood loss, transfusion, erythropoietin or other erythropoiesis-stimulating therapy, kidney failure or hemodialysis, pregnancy, G6PD deficiency, HIV, liver disease and hemoglobin variants can alter interpretation. HbSS, HbCC, HbSC and other states without normal HbA require particular caution. Results may be falsely high or low depending on red-cell biology and the assay-specific interference.
What to do when results disagree
A marked mismatch between A1C and glucose or CGM should prompt investigation of interference, the laboratory method and hemoglobin variants. Plasma-glucose diagnostic criteria may be appropriate for diagnosis; BGM, CGM, fructosamine or glycated albumin may help monitoring in selected contexts. This page does not choose a substitute test or treatment.
References
- Nathan DM, et al. Translating the A1C assay into estimated average glucose values. Diabetes Care. 2008;31(8):1473–1478. PMID 18540046. PMCID PMC2742903. DOI 10.2337/dc08-0545.
- American Diabetes Association Professional Practice Committee for Diabetes. 2. Diagnosis and Classification of Diabetes: Standards of Care in Diabetes—2026. Diabetes Care. 2026;49(Suppl 1):S27–S49. PMID 41358893. PMCID PMC12690183. DOI 10.2337/dc26-S002.
- American Diabetes Association Professional Practice Committee for Diabetes. 6. Glycemic Goals, Hypoglycemia, and Hyperglycemic Crises: Standards of Care in Diabetes—2026. Diabetes Care. 2026;49(Suppl 1):S132–S149. PMID 41358894. PMCID PMC12690178. DOI 10.2337/dc26-S006.
- National Glycohemoglobin Standardization Program. HbA1c and Estimated Average Glucose (eAG).
- National Glycohemoglobin Standardization Program. IFCC Standardization of HbA1c.
- National Glycohemoglobin Standardization Program. Factors that Interfere with HbA1c Test Results.
- National Institute of Diabetes and Digestive and Kidney Diseases. The A1C Test & Diabetes.
- National Institute of Diabetes and Digestive and Kidney Diseases. Sickle Cell Trait & Other Hemoglobinopathies & Diabetes.
FAQ
HbA1c measures the proportion of hemoglobin that is glycated. It indirectly reflects average glycemia over roughly the prior 2–3 months, with recent weeks contributing more heavily, but it does not show individual glucose excursions or hypoglycemia.
The 2008 ADAG regression translates NGSP HbA1c to eAG: eAG in mg/dL equals 28.7 times A1C minus 46.7, and eAG in mmol/L equals 1.5944 times A1C minus 2.594. eAG is a study-derived estimate, not a directly measured average.
No. eAG is a population regression estimate. An individual’s measured mean glucose, CGM mean glucose or glucose management indicator may differ, and eAG does not show time in range, variability, post-meal peaks or hypoglycemia.
IFCC mmol/mol equals 10.93 times NGSP percent minus 23.50. NGSP percent equals 0.09148 times IFCC mmol/mol plus 2.152. The calculator retains unrounded intermediate values.
For appropriate nonpregnant diagnostic contexts, below 5.7% or 39 mmol/mol is below the prediabetes threshold, 5.7–6.4% or 39–47 mmol/mol is the prediabetes range, and at least 6.5% or 48 mmol/mol is the diabetes threshold. An NGSP-certified, DCCT-traceable laboratory method is required.
Not generally. In the absence of unequivocal hyperglycemia, diagnosis requires confirmatory testing with an appropriate laboratory method. This calculator provides threshold context and cannot establish a diagnosis.
A1C cannot determine diabetes type and should not be used alone to diagnose gestational diabetes. Symptoms, pregnancy-specific testing, plasma glucose and the full clinical context are required.
ADA 2026 describes below 7% as a general goal for many nonpregnant adults with diabetes, not a universal target. Goals are individualized for hypoglycemia risk, age, functional status, comorbidities, life expectancy, treatment burden and personal priorities; this page does not recommend medication changes.
For people with stable glycemia who are meeting goals, A1C is commonly measured about twice yearly. When goals are not met, treatment changes or glycemia is unstable, assessment about every 3 months is commonly appropriate, subject to the clinical plan.
Altered red-cell survival or production can make A1C falsely high or low. Examples include hemolytic or iron-deficiency anemia, recent blood loss, transfusion, kidney failure, dialysis, pregnancy, erythropoietin therapy, G6PD deficiency, HIV and liver disease. Direction and magnitude depend on the mechanism and assay.
Hemoglobin variants can cause method-dependent analytic interference or change red-cell survival. HbSS, HbCC, HbSC and other conditions without normal HbA require particular caution. The laboratory method and NGSP interference information should be reviewed.
Investigate red-cell or assay interference, the laboratory method and hemoglobin variants. Plasma-glucose criteria may be used for diagnosis, while BGM, CGM, fructosamine or glycated albumin may be considered for monitoring in an appropriate clinical context. This page does not select a test or treatment.
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Disclaimer
Educational and informational reference only. Not intended to replace professional medical advice, diagnosis, treatment, or independent verification.