M+QuickMedCalc
Educational reference only. Not a diagnostic tool. See full disclaimer.
PulmonaryOxygenation Index

Oxygenation Index Calculator

Calculate oxygenation index from FiO₂, mean airway pressure, and PaO₂.

Content updated: View sources

cm H₂O
mmHg

Oxygenation Index

Reference index; no intervention is selected

Normalized FiO₂:

About

Oxygenation Index (OI) combines inspired oxygen, mean airway pressure, and arterial oxygen tension. It is mainly used as a reference measure of oxygenation impairment in mechanically ventilated patients; age-group definitions and thresholds are not interchangeable.

Formula

OI = FiO₂ (decimal) × mean airway pressure (cm H₂O) × 100 ÷ PaO₂ (mmHg)
Percentage FiO₂ is divided by 100 before calculation

Interpretation

What the result represents: Oxygenation impairment adjusted for both inspired oxygen and mean airway pressure.

Input units: FiO₂ must be explicitly selected as decimal (0.21–1.00) or percent (21–100%); mean airway pressure is cm H₂O and PaO₂ is mmHg.

Worked example: FiO₂ 0.60, mean airway pressure 12, and PaO₂ 60 gives OI = 12.0.

Applicable population: Mechanically ventilated patients with reasonably contemporaneous ventilator data and arterial blood gas measurement.

Interpretation limitations: Neonatal, pediatric, and adult frameworks use different contexts and thresholds. A single value does not determine intubation, ventilator adjustment, ECMO, or another intervention.

References

  1. Emeriaud G, et al. PALICC-2 executive summary: pediatric ARDS diagnosis and management. Pediatr Crit Care Med. 2023.
  2. DesPrez K, et al. Oxygenation Saturation Index Predicts Clinical Outcomes in ARDS. Chest. 2017;152:1151-1158.

FAQ

Related Calculators

Disclaimer

Educational and informational reference only. Not intended to replace professional medical advice, diagnosis, treatment, or independent verification.