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Creatinine Clearance (Cockcroft-Gault)

Input

years
mg/dL

Creatinine Clearance

About

Creatinine clearance (CrCl) estimates kidney function and is commonly used for drug dosing adjustments. The Cockcroft-Gault equation estimates CrCl from serum creatinine, age, weight, and sex. Unlike eGFR, this value is not normalized to body surface area, making it particularly useful for drug dosing in clinical practice.

Formula

CrCl = [(140 − Age) × Weight (kg)] / [72 × Serum Creatinine (mg/dL)]
If female: multiply result by 0.85

Interpretation

CrCl (mL/min)Kidney Function
≥ 90Normal
60 – 89Mild decrease
30 – 59Moderate decrease
15 – 29Severe decrease
< 15Kidney failure

References

  1. Cockcroft DW, Gault MH. Prediction of creatinine clearance from serum creatinine. Nephron. 1976;16(1):31-41.

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Disclaimer

For educational and informational purposes only. Not intended to replace professional medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional.