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CardiologyFramingham

Framingham Risk Score Calculator (2008 General CVD)

Calculate the 2008 lipid-based Framingham Risk Score for 10-year General CVD in adults aged 30–74 without established cardiovascular disease.

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Model check: this page calculates the 2008 lipid-based Framingham General CVD model. It does not calculate Hard CHD, BMI Framingham, Canadian modified FRS, or PREVENT. [1, 2]

The original historical equation has two coefficient branches; this is not a gender-identity determination and the page does not infer a branch.

years

Continuous ages from 30 through 74 are accepted.

unit
unit
mmHg

10-year Framingham general CVD estimate

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Population-model estimate of a first broad general CVD event; no treatment instruction is assigned.

About

This Framingham Risk Score calculator exactly reproduces the D’Agostino 2008 lipid-based continuous General Cardiovascular Disease Risk Profile. It estimates a 10-year population-model probability of a first broad General CVD event for adults aged 30–74 without established cardiovascular disease. It does not calculate Hard CHD, the BMI-based Framingham model, Canadian modified FRS, PREVENT, heart age, or 30-year risk. [1, 2]

Formula

Risk = 1 − S₀(10)^exp(ΣβX − mean coefficient sum). [1, 2]
Male branch: S₀(10) = 0.88936; mean coefficient sum = 23.9802. Female branch: S₀(10) = 0.95012; mean coefficient sum = 26.1931. [1]
The continuous equation uses ln(age), ln(total cholesterol), ln(HDL), treated or untreated ln(SBP), current smoking, and diabetes. [1, 2]
When mmol/L is selected, both cholesterol values are divided by 0.02586 to obtain mg/dL before the original equation is applied. [1]

Interpretation

2008 General CVD endpoint

The first general CVD composite includes coronary death, myocardial infarction, coronary insufficiency, angina, ischemic stroke, hemorrhagic stroke, transient ischemic attack, peripheral artery disease, and heart failure. It is not an ASCVD-only, Hard CHD, or cardiovascular-mortality estimate. [1, 2]

General CVD vs Hard CHD

Hard CHD Framingham calculators estimate a narrower coronary endpoint. This page estimates the broader 2008 General CVD composite, so percentages from the two models are not interchangeable. No Hard CHD result is calculated here. [1, 2]

Current U.S. PREVENT context

The Framingham result is a named historical General CVD model estimate. For current U.S. primary-prevention lipid decisions, the 2026 ACC/AHA dyslipidemia guideline uses PREVENT-ASCVD. Use the separate ASCVD Risk calculator for that different task; this page does not convert Framingham into PREVENT or assign a statin recommendation. [3, 4]

Canadian modified FRS is separate

Current Canadian guidance uses FRS or CLEM, and the CCS publishes a modified FRS pathway. Its FRS tool includes family-history handling and heart age that are not part of this frozen original continuous equation. This page does not apply Canadian modifications, Canadian risk categories, or Canadian treatment thresholds. [5, 6]

Eligibility and limitations

The original equation applies to adults aged 30–74 without established CVD at baseline and estimates a first event. It is not for secondary prevention, pregnancy, automatic treatment selection, or extrapolation outside its development age range. The historical male and female coefficient branches are model inputs, not a determination of gender identity; the page does not infer a branch. Current measurements also do not establish an individual's future outcome or the causal benefit of changing one input. [1, 2]

References

  1. D'Agostino RB Sr, et al. General cardiovascular risk profile for use in primary care. Circulation. 2008. PMID 18212285; DOI 10.1161/CIRCULATIONAHA.107.699579.
  2. Framingham Heart Study. Cardiovascular Disease (10-year risk): official risk-function page.
  3. 2026 ACC/AHA multisociety dyslipidemia guideline. DOI 10.1161/CIR.0000000000001423.
  4. American Heart Association. PREVENT equations and calculator overview.
  5. Canadian Cardiovascular Society. 2021 guideline: overview of dyslipidemia management in primary prevention.
  6. Canadian Cardiovascular Society. Framingham Risk Score calculator and current printable tool.

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Disclaimer

Educational and informational reference only. Not intended to replace professional medical advice, diagnosis, treatment, or independent verification.