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GeneralA/G Ratio

Albumin-to-Globulin Ratio Calculator

Calculate the albumin-to-globulin ratio from measured or calculated globulin.

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Albumin-to-globulin ratio

Laboratory protein ratio; no diagnostic category is assigned

Normalized albumin: g/dL · globulin: g/dL · total protein: g/dL

About

The albumin-to-globulin (A/G) ratio compares serum albumin with the measured or calculated non-albumin protein fraction. It is laboratory arithmetic, not a stand-alone diagnosis.

Formula

A/G ratio = albumin ÷ globulin
Calculated globulin = total protein − albumin

Interpretation

What the result represents: A unitless comparison of albumin with globulin.

Input units: Albumin and globulin or total protein may each be entered in g/dL or g/L; each is explicitly converted to g/dL.

Worked example: Albumin 4.0 g/dL and globulin 2.5 g/dL gives 1.60. Albumin 4.0 and total protein 6.5 gives the same result.

Applicable population: Laboratory reference use when serum protein measurements from a compatible panel are available.

Interpretation limitations: Reference intervals depend on laboratory method and population. Interpret the ratio with the absolute albumin, globulin, and total protein values; it does not by itself identify liver disease, kidney disease, nutrition status, inflammation, or immunoglobulin disorders.

References

  1. Busher JT. Serum Albumin and Globulin. Clinical Methods. 3rd ed. NCBI Bookshelf.
  2. MedlinePlus. Total Protein and Albumin/Globulin (A/G) Ratio.

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Disclaimer

Educational and informational reference only. Not intended to replace professional medical advice, diagnosis, treatment, or independent verification.