Bicarbonate Deficit Calculator
Estimate a static bicarbonate deficit with an explicit distribution factor.
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Estimated bicarbonate deficit
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Static arithmetic estimate; not a dose recommendation
Distribution factor used: — · Weight used: — kg
About
This calculator applies a commonly used static estimate of bicarbonate deficit using body weight, the difference between target and measured bicarbonate, and an explicitly selected distribution factor. The factor is an approximation rather than a fixed physiologic constant, and the result is not a sodium bicarbonate dose or treatment plan.
Formula
Interpretation
Units: Bicarbonate in mmol/L is numerically equivalent to mEq/L. Pounds are converted to kilograms before calculation.
Worked example: At 70 kg, measured HCO₃⁻ 12 mEq/L, target 24 mEq/L, and factor 0.5, the static estimate is 0.5 × 70 × 12 = 420 mEq.
Limitations: Apparent bicarbonate distribution changes with acidemia and buffering. Cause, pH, ventilation, volume status, ongoing losses or acid production, and serial monitoring are not represented. No product, dose, or infusion rate is recommended.
References
- Adrogué HJ, Madias NE. Management of life-threatening acid-base disorders. N Engl J Med. 1998;338:26-34.
- Kraut JA, Madias NE. Metabolic Acidosis: Pathophysiology, Diagnosis and Management. Nat Rev Nephrol. 2010;6:274-285.
- Berend K, de Vries APJ, Gans ROB. Physiological Approach to Assessment of Acid-Base Disturbances. N Engl J Med. 2014;371:1434-1445.
FAQ
Disclaimer
Educational and informational reference only. Not intended to replace professional medical advice, diagnosis, treatment, or independent verification.