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Gastroenterology & HepatologyMELD 3.0

MELD 3.0, MELD-Na & Classic MELD Calculator

Calculate current OPTN MELD 3.0 or reproduce historical MELD-Na and classic MELD using version-specific inputs, bounds and limitations.

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Formula and medical content are based on the references listed on this page. See sources, About, and Sources and Review Process.

Current OPTN MELD is listed first; no model is selected by default.

About

This educational page reproduces current U.S. OPTN MELD arithmetic (MELD 3.0) from the current policy model and calculator context, including its bilirubin, INR, creatinine, sodium, albumin, registration-age, and adult-formula sex branches. [5, 6, 7]

It also separately reproduces historical U.S. MELD-Na or classic MELD from the selected model branch; these are version-specific arithmetic, not an official candidate record. The page does not submit data to OPTN or calculate Status 1A/1B, exception points, listing, organ allocation, referral, or treatment. Formal allocation uses transplant-center-submitted data and the current OPTN system. [1, 2, 4, 8, 9, 10, 11]

Formula

Current OPTN MELD (MELD 3.0) uses bilirubin, INR, creatinine, sodium, albumin, registration-age branch, and adult-formula sex only when registered age 18 or older. [5, 6, 7]
Historical MELD-Na = MELD + 1.32 × (137 − sodium) − 0.033 × MELD × (137 − sodium), only when initial classic MELD is greater than 11. [3, 4, 8]
Classic MELD = 10 × [0.957 × ln(creatinine) + 0.378 × ln(bilirubin) + 1.120 × ln(INR) + 0.643]. [1, 2, 4]

Interpretation

Current OPTN MELD versus historical models

Current U.S. OPTN MELD is a reproduction of Policy 9.1.D arithmetic. Historical MELD-Na was used from 2016 to July 2023, and Classic MELD predates the sodium adjustment. Different versions should not be treated as one directly comparable trend. [4, 6, 8]

Registration age and adult-formula sex

The current model has distinct equations for people registered at age 18 or older and people registered before age 18 who are now at least 12. Adult-formula sex is requested only for the former branch; younger than 12 is outside this page and uses PELD in the applicable official pathway. [5, 6]

Model transformations are not reference ranges

Formula floors, the current creatinine cap at 3.0, historical creatinine rules, sodium 125–137, albumin 1.5–3.5, and scores 6–40 are model transformations. The visible technical product input limits are not healthy ranges, transplant standards, or treatment targets. [4, 5, 6]

Renal-support wording

The current creatinine override requires at least two dialysis treatments or at least 24 hours of CVVHD within seven days before the serum creatinine test. A generic history of dialysis is not enough for this arithmetic branch. [4, 6, 7]

Laboratory and policy limitations

Use one coherent clinical laboratory update. Anticoagulation can affect INR; albumin infusion, laboratory method, and sampling time can affect inputs. Exception scores, NLRB review, Status 1A/1B, and non-U.S. allocation rules are outside this page. [9, 10, 11]

References

  1. Kamath PS, et al. A model to predict survival in patients with end-stage liver disease. Hepatology. 2001;33:464–470. PMID 11172350. DOI 10.1053/jhep.2001.22172.
  2. Wiesner R, et al. MELD and allocation of donor livers. Gastroenterology. 2003;124:91–96. PMID 12512033. DOI 10.1053/gast.2003.50016.
  3. Kim WR, et al. Hyponatremia and mortality among patients on the liver-transplant waiting list. N Engl J Med. 2008;359:1018–1026. PMID 18768945. DOI 10.1056/NEJMoa0801209.
  4. HRSA/OPTN. Revisions to NLRB Notice (January 25, 2019), preserving historical MELD/MELD-Na allocation rules, including the classic formula, creatinine 4.0 mg/dL and qualifying dialysis rule, sodium 125–137 bounds, initial MELD >11 condition, and 1.32/0.033 sodium equation.
  5. Kim WR, et al. MELD 3.0. Gastroenterology. 2021;161:1887–1895.e4. PMID 34481845. PMCID PMC8608337. DOI 10.1053/j.gastro.2021.08.050.
  6. OPTN Policies, Policy 9.1.D MELD Score (policy PDF updated June 24, 2026).
  7. HRSA/OPTN MELD calculator, reviewed December 2025.
  8. HRSA/OPTN July 13, 2023 scoring implementation notice.
  9. HRSA/OPTN liver allocation and exception context.
  10. AASLD/AST liver-transplant evaluation guideline. PMID 24716201.
  11. AASLD acute liver failure context. PMID 22069336.

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Disclaimer

Educational and informational reference only. Not intended to replace professional medical advice, diagnosis, treatment, or independent verification.